| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[6] Paracetamol, oral: NICE Clinical Guideline-Feverish illness in children: assessment and initial management in children younger than 5 years, May 2013. http://www.nice.org.uk/guidance/cg160/chapter/recommendations