| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[5] Antibiotic therapy (candidaemia): Takesue Y, Ueda T, Mikamo H, Oda S, Takakura S, Kitagawa Y, Kohno S; ACTIONs Project. Management bundles for candidaemia: the impact of compliance on clinical outcomes. J AntimicrobChemother. 2015 Feb;70(2):587-93. http://www.ncbi.nlm.nih.gov/pubmed/25326087