| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[26] Amoxicillin, oral: Pattinson RC, Makin JD, Funk M, Delport SD, Macdonald AP, Norman K, Kirsten G,Stewart C, Woods D, Moller G, Coetzee E, Smith P, Anthony J, Schoon M, Grobler S. The use of dexamethasone in women with preterm premature rupture of membranes--a multicentre, double-blind, placebo-controlled, randomised trial. Dexiprom StudyGroup. S Afr Med J. 1999 Aug;89(8):865-70. http://www.ncbi.nlm.nih.gov/pubmed/10488363
Metronidazole, oral: Pattinson RC, Makin JD, Funk M, Delport SD, Macdonald AP, Norman K, Kirsten G,Stewart C, Woods D, Moller G, Coetzee E, Smith P, Anthony J, Schoon M, Grobler S. The use of dexamethasone in women with preterm premature rupture of membranes--a multicentre, double-blind, placebo-controlled, randomised trial. Dexiprom StudyGroup. S Afr Med J. 1999 Aug;89(8):865-70. http://www.ncbi.nlm.nih.gov/pubmed/10488363