| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[8] Bimatoprost 0.01%, ophthalmic drops: National Department of Health: Affordable Medicines, EDP-Adult Hospital level. Evidence summary: Bimatoprost 0.01% vs 0.03% for glaucoma, August 2019. http://www.health.gov.za/
Bimatoprost 0.01%, ophthalmic drops: Katz LJ, Cohen JS, Batoosingh AL, Felix C, Shu V, Schiffman RM. Twelve-month, randomized, controlled trial of bimatoprost 0.01%, 0.0125%, and 0.03% in patients with glaucoma or ocular hypertension. Am J Ophthalmol. 2010 Apr;149(4):661-671.e1. https://www.ncbi.nlm.nih.gov/pubmed/20346780