T88.3
- Dantrolene IV, 2.5 mg/kg as a single dose (preferably through large bore cannula).
- Reconstitute with 60 mL water for injection. For a 70 kg patient, 175 mg (9 vials) is required.
- Administer subsequent doses to clinical effect (cardiac and respiratory symptoms stabilise, muscle tone and body temperature reduced).
- Doses higher than 10 mg/kg is uncommon and the clinician should question the diagnosis.
- Although, high doses of 10 mg/kg may be required in muscular males.